Eduard Bentea

Eduard-Mihai.Bentea@vub.be

024774501

Excitatory neurotransmission relies on a carefully controlled pattern of glutamate release and uptake from the extracellular space that together dictate the concentration of glutamate at (extra)synaptic sites. The cystine/glutamate antiporter system xc- is an example of a poorly understood mediator of constitutive and abundant glutamate release that has the propensity to shape synaptic transmission. Due to its glial localization, system xc- releases glutamate at extrasynaptic sites and is a source of tonic activation of extrasynaptic glutamate receptors. During my post-doctoral research, I investigate the role of system xc- in shaping synaptic communication, with particular focus on the corticostriatal pathway.

 Researchgate profile Eduard Bentea

Research themes

Glutamate Transporters