Cognitive dysfunctions in Parkinson’s disease

PI: Eric Kerckhofs; Natacha Deroost

Apart from the typical motor symptoms, it has become evident in the last decennia that patients with Parkinson’s disease (PD) suffer from non-motor impairments including cognitive dysfunctions. Our research team, linking together the laboratories of cognitive psychology (N. Deroost) and neurological rehabilitation (E. Kerckhofs), investigates motor learning in patients with PD bridging those two domains. More concretely the capacity for (implicit) learning of motor sequences is examined in relation to the progression of the disease. Also the effect of brain modulation by transcranial direct current stimulation on implicit sequence learning is studied. In a large interuniversity research program the role of cognitive impairment in freezing of gait was examined (PhD study of Dr. Jochen Vandenbossche).